There is a need to foster the next generation of clinical researchers in South Africa who will follow through and build upon the critical scientific work being done.

At the PHRU, our succession plan is to invest in promising new scientific investigators by identifying, training, mentoring and exposing them to valuable career opportunities. This is so that we can retain and sustain high quality researchers who will serve the health research needs of South Africa and the world.

Our Publications Coaching Programme, launched on 11/11/11, is an innovative scientific writing programme founded by Dr Fatima Laher (medical researcher), Dr Janan Dietrich (sociobehavioural scientist) and Prof Kennedy Otwombe (biostatistical researcher). The Programme provides promising new investigators with scientific writing theory and coaching. The aims are to build capacity, pass on skills pertinent to a research environment, increase publication output, inspire scientific curiosity and develop a succession line of new scientists.

The programme has in the past received part-funding from SPARC and the Canadian African Prevention Trials Network. Read more about the programme in Dietrich J, Otwombe K, Heritage T, Coetzee J, Lazarus E, Meyer Z, Laher F. Nurturing a new generation of scientific writers in Soweto, South Africa. Open Medicine 2013;7(3 Suppl):s63.

Entering the ninth year of the Publications Coaching Programme, we celebrate some of our accomplished alumni who have published important science:

Dr Limakatso Lebina, Class of 2012

26 Pubmed-listed publications so far; her first ever publication was written with the Publications Coaching Programme: Lebina L, Laher F, Mukudu H, Essien T, Otwombe K, Gray G, Martinson N. Does routine prophylactic oral flucloxacillin reduce the incidence of post-circumcision infections? Am J Infect Control. 2013 Oct;41(10):897-900. doi: 10.1016/j.ajic.2012.12.015. Epub 2013 Mar 13. PubMed PMID: 23489735.

Dr Haseena Cassim, Class of 2014

5 Pubmed-listed publications so far; her first first-author publication was written with the Publications Coaching Programme: Cassim H, Otwombe K, Lazarus E, Liberty A, Gray GE, Greeff OBW, Violari A. A retrospective case-cohort study comparing treatment outcomes in abacavir versus stavudine containing first line antiretroviral treatment regimens in children <3yrs old, at a paediatric programme based in Soweto, South Africa. PLoS One. 2017 Jul 7;12(7):e0180645. doi: 0.1371/journal.pone.0180645. eCollection 2017. PubMed PMID: 28686654; PubMed Central PMCID: PMC5501584.

Stefanie Hornschuh, Class of 2014

5 Pubmed-listed publications so far; her publication written with the Publications Coaching Programme was: Hornschuh S, Laher F, Makongoza M, Tshabalala C, Kuijper LDJ, Dietrich J. Experiences of HIV-positive adolescents and young adults in care in Soweto, South Africa. (2014) Journal of HIV/AIDS & Social Services, 13:4, 420-435, DOI: 10.1080/15381501.2013.804472

Kate Hopkins (nee Cerwensky), Class of 2013

5 Pubmed-listed publications so far; her first first-author publication was written with the Publications Coaching Programme: Hopkins KL, Laher F, Otwombe K, Churchyard G, Bekker LG, DeRosa S, Nchabeleng M, Mlisana K, Kublin J, Gray G. Predictors of HVTN 503 MRK-AD5 HIV-1 gag/pol/nef vaccine induced immune responses. PLoS One. 2014 Aug 4;9(8):e103446. doi:10.1371/journal.pone.0103446. eCollection 2014. PubMed PMID: 25090110; PubMed Central PMCID: PMC4121165.

Dr Hilary Mukudu, Class of 2014

2 Pubmed-listed publications so far; his first first-author publication was written with the Publications Coaching Programme: Mukudu H, Otwombe K, Laher F, Lazarus E, Manentsa M, Lebina L, Mapulanga V Bowa K, Martinson N. A Cross Sectional Study of the Prevalence of Preputial and Penile Scrotal Abnormalities among Clients Undergoing Voluntary Medical Male Circumcision in Soweto, South Africa. PLoS One. 2016 Jun 2;11(6):e0156265. doi:10.1371/journal.pone.0156265. eCollection 2016. PubMed PMID: 27253372; PubMed Central PMCID: PMC4890756.

Dr Jesne Kistan, Class of 2015

2 Pubmed-listed publications so far; her publication with the Publications Coaching Programme was Kistan J, Laher F, Otwombe K, Panchia R, Mawaka N, Lebina L, Diacon A, Kana B, Martinson N. Pulmonary TB: varying radiological presentations in individuals with HIV in Soweto, South Africa. Trans R Soc Trop Med Hyg. 2017 Mar 1;111(3):132-136. doi: 10.1093/trstmh/trx028. PubMed PMID: 28633335.

Sakhile Mhlongo, Class of 2012

2 Pubmed-listed publications so far; his publication written with the Publications Coaching Programme was Mhlongo S, Dietrich J, Otwombe KN, Robertson G, Coates TJ, Gray G. Factors associated with not testing for HIV and consistent condom use among men in Soweto, South Africa. PLoS One. 2013 May 16;8(5):e62637. doi:10.1371/journal.pone.0062637. Print 2013. PubMed PMID: 23696786; PubMed Central PMCID: PMC3656000.

Please see below a list of the2013 Publications

 

A qualitative analysis of factors influencing HPV vaccine uptake in Soweto

A viable sample and self-sampling method

Cautious optimism for HIV vaccine science

Concordant oral-genital HPV infection in South African couples

Conference Proceedings

Cost-effectiveness of HIV Treatment

Costs of inpatient treatment for multi-drug-resistant tuberculosis in South Africa

Daily acyclovir to decrease Herpes Simplex virus type 2

Does participation in an HIV vaccine efficacy trial affect

Does routine prophylactic oral flucloxacillin reduce

Early-time limited antiretroviral therapy

Effect of in-utero HIV exposure and antiretroviral

Efficacy and immunogenicity of influenza vaccine

Estimation of HIV incidence in a large community-based randomized clinical trial

Factors associated with not testing for HIV

High prevalence of pulmonary tuberculosis

HIV testing and counselling leads to immediate consistent condom use

Identification and characterization of vaginal lactobacilli from

Immunogenicity following the first and second doses

KIR2DS4 allelic variants

Lamivudine monotherapy as a holding stratergy

Loss to follow-up among infants in a study of isoniazid prophylaxis

Mobile VCT - Reaching men and young people

Mortality associated with delays between clinic entry and ART

Multiple levels of influence in predicting sexual activity and condom use

Not credited - association of Pol diversity

Oral and injectable contraceptives use

Partner characteristics predicting HIV-1 set point in sexually acquired HIV-1

Poor early virologic perfomance and durability of

Predictors of delay in the diagnosis and treatment of

Prevalence of Tobacco smoking in adults

Promoting safe infant feeding practices

Proof of peer review - Women Motherhood and Living

Rates and Cost and frequency of hospitalisation before and after ART initiation in SA

Requesting for proof of peer review process

Request for proof of peer review process

After fi rst-line ART: towards an evidence-based SECOND-LINE

Ritonavir-boosted lopinavir plus nucleoside or nucleotide reverse transcriptase inhibitors versus ritonavir-boosted lopinavir plus raltegravir for treatment of HIV-1 infection in adults with virological failure of a standard fi rst-line ART regimen (SECOND-LINE): a randomised, open-label, non-inferiority study

The clinical and economic impact of genotype testing at first-line antiretroviral therapy failure for HIV-infected patients

Undisclosed antiretroviral drug use in a multinational clinical trial

Violari A - Association for pol Diversity

Whoonga and the Abuse and Diversion of Antiretrovirals in Soweto, South Africa

Wits-2014-001898

 

Please see below a list of the2014 Publications

 

Adolescent experiences of HIV

Adolescent experiences of HIV and sexual health communication with parents and caregivers in Soweto

Adolescent friendly technologies as potential adjuncts for health promotion

Assessing cost and technical efficiency of HIV prevention interventions in sub Saharan Africa

A comparative assessment of price brand

A Review of the study designs

CD4 and viral load dynamics in antiretroviral-naive HIV-infected adults from Soweto

CD4 Counts and viral loads of newly diagnosed HIV-infected individuals - implications for treatment as prevention

Correlates of sexual risk among sexual minority and heterosexual South African youth

Cotrimoxazole prophylaxis and Tuberculosis risk

Early severe HIV disease precedes early antiretroviral therapy in infants - Are we too late

Effect of community-based voluntary counselling and testing on HIV incidence and social and behavioural outcomes

Effect of HIV 1 exposure and antiretroviral

Enhanced and persistent antibody response against homologous and heterologous strains

Experiences of HIV-positive adolescents and young adults in care in Soweto South Africa

Factors associated with mortality in HIV-infected people

Frequent genital HSV-2 shedding among women during labor in Soweto

Global evidence reaffirms the case for routine HPV and potential HIV adolescent vaccination in South Africa

Implementation of isoniazid preventive therapy for HIV-infected adults - overstatement

Incidence of TB and HIV in prospectively

The association between the ratio of monocytes

The effect of topical calcipotriol or zinc on tuberculin skin tests in hospitalised South African children

The HVTN503-Phambili HIV vaccine trial - A comparison for younger and older participants

Toll-like receptor polymorphism associations with HIV-1 outcomes among sub-Saharan Africans

Understanding treatment refusal among adults presenting for hig-testing in Soweto South Africa A qualitative study

Unreported antiretroviral use by HIV-1 infected participants enrolling in a prospective research study

Uptake of genital mucosal sampling in HVTN 097 a phase 1b hiv vaccine trial in South Africa

Variants in host viral replication cycle genes are associated with heterosexual HIV-1 acquisition in Africans

Woonga and the abuse and diversion of antiretroviral in Soweto

Please see below a list of the 2012 Publications

 

Anticipated changes in sexual risk behaviour following vaccination with a low-efficacy HIV vaccine

Assessment of service availability and health care workers opinion about young womens sexual reproductive health in Soweto

A qualitative study of obstacles to diaphragm and condom use

Causes of death on antiretroviral therapy - a post-mortem study from South Africa

Community-based targeted case findings for Tuberculosisand HIV in household contacts of patients with Tuberculosis in South Africa

Conversations with mothers - exploring reasons exploring reasons for prevention of mother-to-child transmission

Designing family-centred male circumcision services - a conjoint analysis approach

Determinants of per coital-act HIV 1infectivity among African HIV-1 serodiscordant couples

Does early initiation of ART in infants

Early antiretroviral therapy improves neurodevelopmental outcomes in infants

Eliminating paediatric infections and keeping mothers alive

Elite controllers - Understanding natural suppressive control of HIV-1 infection

Health Diplomacy and adapting global health interventions to local needs - findings from project ACCEPT HPTN043

Hepatitis B Virus Infection in Human Immunodeficiency Virus Infected S.A Adults

High Level of Agreement between clinician -collected and self-collected samples for HPV detection among South African Adolescents

High prevalence of drug resistance amongst HIV-exposed and infected children on a tuberculosis prevention trial

HIV and the urban homeless in Johannesburg

HIV Vaccine trial safety and retention

Increased Differentiation associates with decreased polyfuctinality for HIV - G De Bruyn

Increased regression and decreased incidence of HPV-related cervical lesions among HIV-infected women on HAART

Key Issues in the clinical development and implemantation of TB vaccines in S A

Maternal antiretroviral prophylaxis and breastfeeding

Mortality in members of HIV-1 serodiscordant couples in Africa and implications for antiretroviral therapy initiation

Nevirapine- versus Lopinavir-Ritonavir-based initial therapy for HIV-1 infection among women in Africa

Nevirapine versus ritonavir -boosted lopinavir for HIV-Infected children

Pilot study on the immunogenicity of paired Env immunogens from mother-tochild transmitted HIV-1 isolates

Preexposure prophlaxis for HIV prevention

Pregnancy incidence and Correlates during the HVTN 503 Phambili HIV vaccine trial conducted among South African women

Prevelance and associations with Hepatitis B and Hepatitis C Infection among HIV infected adults in SA

Quantifying ongoing HIV-1 exposure in HIV-1-serodiscordant couples to identify individuals with potential host resistance to HIV-1

Screen failure in Phase 1 HIV clinical trials in Soweto S.A an opportunity for care - F Laher

Sexual risk behaviors among HIV-infected South African Men and women with their partners in a primary care program

Short course Combivir after single-dose nevirapine reduces nut does not eliminate the emergence of nevirapine resistance in women

South African HIV-1 vaccine candidates the journey from the bench to clinical trials

Specificity of four laboratory approaches for cross-sectional HIV incidence determination

Stretching delivery of HIV health Services

The medical proof does not get much better than VMMC

Three Postpartum Anteretoviral regimens to prevent intrapartum HIV-infection

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