One of Africa's leading medical and social research centres into Aids and HIV
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2005 Publications

Article Index
2005 Publications
2005 Publications (Part II)
2005 Publications (Part III)
2005 Publications (Part IV)
2005 Publications (Part V)
2005 Publications (Part VI)
All Pages

2003-2005 (PDF format,132kb )


2005 – Papers and publications

PHRU Overview: 1996 to 2005

This report details the achievements of the Perinatal HIV Research Unit’s (PHRU) comprehensive HIV/AIDS research programme over the past 10 years. The report focuses on recent achievements but also provides a brief overview of the earlier days.
Download the report. [PDF, 1.45MB] Use Acrobat Reader version 6 or later.

Journal articles: 2005

Chersich M, Gray G: Progress and emerging challenges in preventing mother-to-child transmission. Curr Infect Dis Rep. 2005 Sep;7(5):393-400. Review.

Coovadia H, Fowler MG, Lockman S, McIntyre J. Roundtable. Revisiting the role of single-dose nevirapine for preventing perinatal HIV transmission. AIDS Clin Care. 2005 Jul;17(7):61-4.

Coplan PM, Gupta SB, Dubey SA, Pitisuttithum P, Nikas A, Mbewe B, Vardas E, Schechter M, Kallas EG, Freed DC, Fu TM, Mast CT, Puthavathana P, Kublin J, Brown Collins K, Chisi J, Pendame R, Thaler SJ, Gray G, McIntyre J, Straus WL, Condra JH, Mehrotra DV, Guess HA, Emini EA, Shiver JW. Cross-reactivity of anti-HIV-1 T cell immune responses among the major HIV-1 clades in HIV-1-positive individuals from 4 continents. J Infect Dis. 2005 May 1;191(9):1427-1434.

Dabis F, Balestre E, Braitstein P, Miotti P, Brinkhof WG, Schneider M, Schechter M, Laurent C, Boulle A, Kabugo C, Capkun G, Seyler C, McIntyre J, Sprinz E, Bangsberg D, Van der Borght S, Egger M; The Antiviral Therpapy in Lower Income Countries (ART-LINC) Study Group. Cohort profile: Antiretroviral therapy in lower income countries (ART-LINC): international collaboration of treatment cohorts. Int J Epidemiol. 2005 Oct;34(5):979-86.

De Bruyn G. Diarrhoea in adults (acute). Clin Evid. 2005 Jun;(13):896-916. Review.

De Bruyn G, Hudgens MG, Sullivan PS, Duerr A. Participant retention in clinical trials of candidate HIV vaccines. J Acquir Immune Defic Syndr. 2005 Aug 1;39(4):499-501.

De Bruyn G, Vargas-Cortez M, Warren T, Tyring SK, Fife KH, Lalezari J, Brady RC, Shahmanesh M, Kinghorn G, Beutner KR, Patel R, Drehobl MA, Horner P, Kurtz TO, McDermott S, Wald A, Corey L. A Randomised controlled trial of a replication defective (gH deletion) herpes simplex virus vaccine for the treatment of recurrent genital herpes among immunocompetent subjects. Vaccine. 2005 Sep 21; In press, online publication Sep 2, 2005.

Gray GE, Urban M, Chersich MF, Bolton C, van Niekerk R, Violari A, Stevens W, McIntyre JA for the PEP Study Group. A randomised trial of two post-exposure prophylaxis regimens to reduce mother-to-child HIV-1 transmission in infants of untreated mothers. AIDS 2005 Aug 12, 19:1289-1297.

Gray CM, Williamson C, Bredell H, Puren A, Xia X, Filter R, Zijenah L, Cao H, Morris L, Vardas E, Colvin M, Gray G, McIntyre J, Musonda R, Allen S, Katzenstein D, Mbizo M, Kuwenda N, Taha T, Karim SA, Flores J, Sheppard HW. Viral Dynamics and CD4 T cell counts in subtype C human immunodeficiency virus type 1-infected individuals from southern Africa. AIDS Res Hum Retroviruses 2005, Apr 21 (4) 285-91.

Jaspan HB, Gray GE, Robinson AK, Coovadia HM, Bekker LG. Scientific justification for the participation of children and adolescents in HIV-1 vaccine trials in South Africa. S Afr Med J. 2005 Sep;95(9):685-7.

Johnson JA, Li JF, Morris L, Martinson N, Gray G, McIntyre J, Heneine W. Emergence of drug-resistant HIV-1 after intrapartum adminstration of single-dose nevirapine is substantially underestimated. J Infect Dis. 2005 Jul 1;192(1):16-23.

Leroy V, Sakarovitch C, Cortina-Borja M, McIntyre J, Coovadia H, Dabis F, Newell ML, Saba J, Gray G, Ndugwa Ch, Kilewo Ch, Massawe A, Kituuka P, Okong P, Grulich A, von Briesen H, Goudsmit J, Biberfeld G, Haverkamp G, Weverling GJ, Lange JM; Ghent Group on HIV in Women and Children. Is there a difference in the efficacy of peripartum antiretroviral regimens in reducing mother-to-child transmission of HIV in Africa? AIDS, 2005 Nov 4; 19(16):1865-75.

Madhi SA, Zar HJ, Saloojee H, Gray GE. Co-trimoxazole prophylaxis in African children with HIV-1. Lancet. 2005 Feb 26;365(9461):749-50. Letter.

McIntyre J. Maternal health and HIV. Reprod Health Matters. 2005 May;13(25):129-35.

McIntyre J. Preventing mother-to-child transmission of HIV: successes and challenges. BJOG. 2005 Sep;112(9):1196-203. Review.

McIntyre JA. Sex, pregnancy, hormones, and HIV. Lancet. 2005 Oct 1;366(9492):1141-2.

McIntyre J. Prevention of mother-to-child transmission of HIV: treatment options. Expert Rev Anti Infect Ther. 2005 Dec;3(6):971-80.

Naeem-Sheik A, Gray G. HIV Disclosure in Children. S Afr J HIV Medicine, Nov 2005: 46-48.

Rose P, Violari A, Bolton C, Gray GE. Feasibility and acceptability of postpartum voluntary counselling and testing (PPVCT) in a large tertiary hospital in the South African setting. S Afr J HIV Medicine, June 2005: (19):8-10. Review.

Swartz L, Bhana A, Gray G, Kafaar Z, et al (2005). Social and behavioural aspects of child and adolescent participation in HIV vaccine trials. J Int Assoc Physicians in AIDS Care, 4(4):89-92.

Vardas E, Butto S, Glashoff R, Malnati MS, Poli G, Clerici M. Preparing for phase II/III HIV vaccine trials in Africa. Microbes Infect. 2005 Nov;7(14):1436-44.